Introduction
IGF-1 LR3, also known as Long-Arginine-3-IGF-1, is an analogue of human IGF-1 that has been modified to include a 13 amino acid N-terminus extension and the substitution of Arginine for Glutamic Acid at position 3. As a result of these modifications, IGF-1 LR3 is approximately three times more potent than IGF-1 and possesses an increased half-life due to lowered affinity for binding to the Insulin-Like Growth Factor-Binding Proteins (IGFBPs). IGF-1 LR3 retains the ability to bind agonistically to the IGF-1 receptor with improved metabolic stability, relative to IGF-1. The supplementation of mammalian cell cultures with Long R3 IGF-1 at a much lower concentration results in more highly elevated productivity than with standard concentrations of insulin and/or standard IGF-1. IGF-1 LR3 is more able to stimulate the type 1 IGF receptor and thus induce a higher level of activation of intracellular signaling, which is responsible for promoting cell proliferation and the inhibition of apoptosis.
IGF-1 LR3 |
|
CAS |
946870-92-4 |
Category |
Peptide |
Quality Standard |
EP/USP |
MSDS |
Available |
Sample |
Available |
MOQ |
1g,1kg |
Delivery Date |
In 3 days |
Place Of Origin |
China |
Application |
Pharmaceutical raw materials |
Function
Using this on cycle and during PCT. increased muscle retention and faster recovery. IGF-1-LR3 will cause even greater elevations in Igf and the potential for more muscle growth and fat loss through its unique ability to drain fat cells and supply muscle cells with vital nutrients.
1) Helps regulate fat for use as energy, resulting in fat loss.
2).Contributes to anti aging. As we get older, IGF-1 production slows down and this
results in cell reduction. Low levels of IGF-1 are linked to heart failure, lower brain
cell regulation and neuron function. Not to mention muscle tissue breakdown.
3).Helps to increase nutrient shuttling (protein synthesis).
4).Increases regenerative functions of nerve tissues.
5).Boosts the ability to cause hyperplasia in muscle cells resulting in fuller muscle
Application
Igf-1 des lr3 builds new muscle tissue by promoting nitrogen retention and protein synthesis. igf-1 des lr3 causes the growth of muscles through both hyperplasia (which is an increase in number of muscle cells) and mitogenesis (which is the actual growth of new muscle fibers). Thus IGF-1 not only makes muscle fibers bigger, it makes more of them as well! IGF-1's effects are not limited to building new muscle, however. It has a potent effect on lipid (fat) metabolism, and helps the body burn fat at a significantly elevated rate. In addition, IGF-1 is both a neuroprotector and neuropromotor, which improves mental functions such as reflexes, memory, and learning ability. IGF is also important for production of connective tissue and insuring proper bone density.