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Reliable quality Myostatin with best price manufacturer

Name Myostatin
Other Name MSTN

Introduction:

Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.

A technique for detecting mutations in myostatin variants has been developed.[24] Mutations that reduce the production of functional myostatin lead to an overgrowth of muscle tissue. Myostatin-related muscle hypertrophy has an incomplete autosomal dominance pattern of inheritance. People with a mutation in both copies of the MSTN gene in each cell (homozygotes) have significantly increased muscle mass and strength. People with a mutation in one copy of the MSTN gene in each cell (heterozygotes) have increased muscle bulk, but to a lesser degree.

Name

GDF-8

Synonyms

Myostatin GDF-8

Molecular Formula:

C221H366N72O67S

CAS

901758-09-6

Appearance

White powder

Origin

China

Application

increase muscle/body building

Purity

99%min

Package`

1MG/vial;10 vials/kit(carton box)/ bulk wholesale in bag/drum package


Function:

1) Myostatin / GDF-8 can effectively prevent the increased due to age brings the increase of adipose tissue, and reduce the occurrence of diabetes and obesity
2) Myostatin / GDF-8 used to treating malnutrition patients is an important index of the strength training athletes
 3) Myostatin / GDF-8 used to treat muscle atrophy, strengthen muscle toughness,Increase muscle number


Application:

The gene encoding myostatin was discovered in 1997 by geneticists Se-Jin Lee and Alexandra McPherron who produced a strain of mutant mice that lack the gene. These myostatin "knockout" mice have approximately twice as much muscle as normal mice. These mice were subsequently named "mighty mice".
Naturally occurring deficiencies of myostatin have been identified in cattle by Ravi Kambadur, whippets, and humans; in each case the result is a dramatic increase in muscle mass. A mutation in the 3' UTR of the myostatin gene in Texel sheep creates target
 sites for the microRNAs miR-1 and miR-206. This is likely to cause the muscular phenotype of this breed of sheep.



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