Introduction:
Ibutamoren (MK-677, L-163,191) is a medicine which acts as a potent, active growth hormonesecretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity.
Chemical Name |
Ibutamoren mesilate |
CAS No. |
159752-10-0 |
Appearance |
White powder |
MF |
C28H40N4O8S2 |
MW |
624.76900 |
MOQ |
1kg |
Sample |
Available |
Boiling Point |
868.9ºC at 760 mmHg |
Flash Point |
479.3ºC |
Vapour Pressure |
3.05E-32mmHg at 25°C |
Function:
1. MK677 acts as a potent, orally active growth hormone secretagogue.
2. MK677 is able to increase both muscle mass and bone mineral density. It also alters metabolism of body fat and so may have application in the treatment of obesity.
Application:
1. Building Muscle
It is frequently used as an anabolic substance, to increase lean body mass i.e. create bigger muscles.
2. Muscle Wasting
It improved gait speed, muscle strength and reduced the number of falls.
3. Bone Density
Ibutamoren increased bone mineral density, which helps increase bone strength and prevent osteoporosis
4.Sleep
It improved sleep quality and REM (rapid eye movement) sleep duration.