MGF is produced biologically when muscle fibers are broken down through resistance (weight training). It is a potent factor in muscle growth. MGF stimulates muscle growth, creates new muscle fibers, promotes nitrogen retention and increases protein synthesis. This compound is commonly used for overall growth of muscle and to promote growth in body parts that are not up to par with the rest of the user’s physique. Results usually depend on dosage. Fat loss and strength increases are not typically seen with MGF’s use (as they are in IGF-1 use).
The PEG itself is safe for use as it is approved by the US Food and Drug Administration (FDA) and does not react in the body. The PEG is not broken down in the body and excreted (intact) through urine or feces. Any risk associated PEGylated drugs is due to drug itself not the PEG per se.
PEG-MGF, or PEGylated Mechano Growth Factor is a new and innovative form of MGF that outperforms natural MGF many times over. MGF is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream. MGF is only stable in the blood stream for only a few minutes.
Growth factor drugs refer to substances that promote cell growth in addition to normal components such as amino acids, vitamins, glucose, and inorganic salts in tissue culture. Most growth factors are peptide hormones in a broad sense, including insulin, epidermal growth factor (EGF), fibroblast growth factor (FGF), platelet-derived growth factor (platelet-derived growth factor, PDGF), and growth hormone release inhibitory factor (somatostatin= SRIH) etc. Growth factors are cytokines with activity to stimulate cell growth.