Introduction:
Thymosin β4 is a 43 amino acid peptide which is regarded as the main intracellular G-actin sequestering peptide. Extracellular thymosin β4 may contribute to physiological processes such as angiogenesis, wound healing, and regulation of inflammation.
Name |
Thymosin Beta-4 |
Reference |
Sh-Oligopeptide-4, TB500 |
CAS No. |
77591-33-4 |
Sequence |
Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser |
Molecular Formula |
C212H350N56O78S |
Molecular Weight |
4963.4408 |
Appearance |
White powder |
Purity(HPLC) |
≥98.0% |
Function:
• Endothelial (blood vessels) cell differentiation
• Angiogenesis (growth of new blood cells from pre-existing vessels) in dermal tissues
• Keratinocyte migration
• Collagen deposition
• Decreases inflammation of tissue in joints
• Increase muscle growth with huge increases in endurance and strength noted
• Relaxed muscle spasm and improved muscle tone
• Increase the exchange of substance between cells
• Encourage tissue repair
• Stretches connective tissue and helps maintain flexibility
• Prevents the formations of adhesions and fibrous bands in muscles, tendons and ligaments
Appllication:
TB-500 is an injectable peptide drug which can be used to promote healing, enhance range of motion in cases of injury, or reduce pain in case of injury by reducing inflammation. As yet its human use has been relatively uncommon and limited to individuals who like to experiment. Use in race horses has been more widespread, though it’s not a prescription veterinary drug.