Peptide hormone is made up of amino acids linked by peptide bonds. The smallest peptide hormone can be composed of three amino acids, such as thyroid stimulating hormone releasing hormone (TRH). Most peptide hormones can be composed of dozens, dozens, or even hundreds and hundreds of amino acids. The main secreting organs of peptide hormones are the hypothalamus and pituitary gland. Peptide hormones are also found in other organs, such as the gastrointestinal tract, brain tissue, lung and heart, most of which are in the research stage.
The role of peptide hormones is to promote the growth and development of the human body by stimulating the growth of the adrenal cortex and red blood cell production. A large intake of them will reduce their own endocrine levels, harm physical health, and may also cause cardiovascular diseases, diabetes, etc. Similarly, the abuse of peptide hormones will also form a strong psychological dependence.
The abuse of anabolic agents and peptide hormones has emerged with the development of modern competitive sports and is becoming more and more serious. With the improvement of people's living standards, the desire for bodybuilding and the popularization of fitness exercises, it has moved to the fields of school sports and social sports. spread. On the one hand, people who abuse such drugs are becoming more common; on the other hand, the age of the abusers is also decreasing, which seriously threatens the physical and mental health of the public, especially young people.
Erythropoietin (EPO) and its analogues, growth hormone (hGH) and its analogues, there is little difference between exogenous drugs (peptide stimulants) and endogenous hormones (naturally produced by the human body), and drug metabolism in the human body Short time and other characteristics, there has been no accurate and reliable detection method for a long time, and it has been widely abused by athletes. It is also a hot drug in the anti-doping struggle. Both EPO and hGH are peptide hormones. Other peptide hormones listed in the prohibited list include: corticotropin, gonadotropin (including luteinizing hormone, chorionic gonadotropin), insulin and its analogs, insulin Like growth factors and so on. Below, we focus on introducing two representative peptide hormone stimulants-EPO and hGH.