Caffeic acid phenethyl ester referred CPAE, is one of the main active component of propolis, the effectiveness of the herpes virus, other viruses were inhibited by propolis components as well as adenovirus, influenza virus. Propolis CAPE, quercetin, isoprene, esters, isorhamnetin, Kora prime and glycosides, polysaccharides and other substances have anticancer activity, can inhibit the proliferation of tumor cells, cancer cells have a certain toxic effect and CAPE tumor cells with specific lethality.
1. Caffeic acid phenethyl ester has been shown to inhibit carcinogenesis, although other experiments show possible carcinogenic effects. It is also known as an antioxidant in vitro and also in vivo.
2. Caffeic acid phenethyl ester also shows immunomodulatory and anti-inflammatory activity.
3. Caffeic acid phenethyl ester outperformed the other antioxidants, reducing aflatoxin production by more than 95 percent. The studies are the first to show that oxidative stress that would otherwise trigger or enhance.Aspergillus flavus aflatoxin production can be stymied by caffeic acid. This opens the door to using natural anti-fungicide methods by supplementing trees with antioxidants.
Caffeic acid phenethyl ester (CAPE) is a natural phenolic chemical compound. It is the ester of caffeic acid and phenethyl alcohol. A variety of in vitro pharmacology and effects in animal models have been reported for CAPE, but their clinical significance is unknown. It has antimitogenic, anticarcinogenic, anti-inflammatory, and immunomodulatory properties in vitro. Another study also showed that CAPE suppresses acute immune and inflammatory responses in vitro. This anti-cancer effect was also seen when mice skin was treated with bee propolis and exposed to TPA, a chemical that induced skin papillomas. CAPE significantly reduced the number of papillomas.